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Target
D(2) dopamine receptor
Ligand
BDBM50034341
Substrate
n/a
Meas. Tech.
ChEBML_59890
Ki
18±n/a nM
Citation
 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Comparison of 5-HT1A and dopamine D2 pharmacophores. X-ray structures and affinities of conformationally constrained ligands. J Med Chem 36:1301-15 (1993) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50034341
Synonyms:
(3aR,9bS)-3-allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole | (3aR,9bS)3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole | CHEMBL280955
Type:
Small organic molecule
Emp. Form.:
C16H21NO
Mol. Mass.:
243.344
SMILES:
COc1cccc2[C@@H]3CCN(CC=C)[C@@H]3CCc12
Structure:
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