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TargetAGTR1
LigandBDBM50368649
Substrate/Competitorn/a
Meas. Tech.ChEMBL_36154
Ki 68±n/a nM
Citation Winn, MDe, BZydowsky, TMAltenbach, RJBasha, FZBoyd, SABrune, MEBuckner, SACrowell, DDrizin, I 2-(Alkylamino)nicotinic acid and analogs. Potent angiotensin II antagonists. J Med Chem36:2676-88 (1993) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
AGTR1
Name:AGTR1
Synonyms:ANGIOTENSIN AT1 | Angiotensin II AT1 | Angiotensin II AT1A | Angiotensin II receptor (AT-1) type-1 | Type-1A angiotensin II receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:40910.53
Organism:RAT
Description:ANGIOTENSIN AT1 AGTR1 RAT::P25095
Residue:359
Sequence:
MALNSSAEDGIKRIQDDCPKAGRHSYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIHRNVYFIENTNITVC
AFHYESRNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFR
IIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCKISDIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPKAKSHSSLSTKMSTLSYRPSDNMSSSAKKPASCFEVE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50368649
n/a
NameBDBM50368649
Synonyms:CHEMBL1202852
TypeSmall organic molecule
Emp. Form.C21H19N7O2
Mol. Mass.401.4213
SMILESCCc1ncc(C(O)=O)c(NCc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)n1
Structure
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