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Target
Cholecystokinin receptor type A
Ligand
BDBM50040517
Substrate
n/a
Meas. Tech.
ChEMBL_49710 (CHEMBL661162)
IC50
707±n/a nM
Citation
 Holladay, MW; Kopecka, H; Miller, TR; Bednarz, L; Nikkel, AL; Bianchi, BR; Witte, DG; Shiosaki, K; Lin, CW; Asin, KE Tetrapeptide CCK-A agonists: effect of backbone N-methylations on in vitro and in vivo CCK activity. J Med Chem 37:630-5 (1994) [PubMed]  Article 
Target
Name:
Cholecystokinin receptor type A
Synonyms:
CCK-A receptor | CCK-AR | CCK1-R | CCKAR | CCKAR_CAVPO | Cholecystokinin A receptor | Cholecystokinin receptor type A | Cholecystokinin-1 receptor
Type:
n/a
Mol. Mass.:
48229.77
Organism:
Cavia porcellus
Description:
n/a
Residue:
430
Sequence:
MDVVDSLFVNGSNITSACELGFENETLFCLDRPRPSKEWQPAVQILLYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPSLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTGNMCRFLLPNDVMQQTWHTFLLLILFLIPGIVMMVAYGLISLELYQGIKFDAIQKKSAKERKTSTGSSGPMEDSDGCYLQKSRHPRKLELRQLSPSSSGSNRINRIRSSSSTANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAERHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGTPGVRGEMGEEEEGRTTGASLSRYSYSHMSTSAPPP
  
Inhibitor
Name:
BDBM50040517
Synonyms:
(S)-3-{[(S)-2-[(S)-2-(tert-Butoxycarbonyl-methyl-amino)-3-(1H-indol-3-yl)-propionylamino]-6-(3-o-tolyl-ureido)-hexanoyl]-methyl-amino}-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid | CHEMBL407507
Type:
Small organic molecule
Emp. Form.:
C45H58N8O9
Mol. Mass.:
854.9902
SMILES:
CN([C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)Nc1ccccc1C)C(=O)N(C)[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O)C(=O)OC(C)(C)C
Structure:
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