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Target
Aminopeptidase B
Ligand
BDBM50036829
Substrate
n/a
Meas. Tech.
ChEMBL_36048 (CHEMBL645580)
Ki
11±n/a nM
Citation
 Chauvel, EN; Coric, P; Llorens-Cortès, C; Wilk, S; Roques, BP; Fournié-Zaluski, MC Investigation of the active site of aminopeptidase A using a series of new thiol-containing inhibitors. J Med Chem 37:1339-46 (1994) [PubMed]  Article 
Target
Name:
Aminopeptidase B
Synonyms:
AMPB_HUMAN | APB | Aminopeptidase | Ap-B | Arginine aminopeptidase | Arginyl aminopeptidase | RNPEP
Type:
PROTEIN
Mol. Mass.:
72586.33
Organism:
Homo sapiens (Human)
Description:
ChEMBL_36048
Residue:
650
Sequence:
MASGEHSPGSGAARRPLHSAQAVDVASASNFRAFELLHLHLDLRAEFGPPGPGAGSRGLSGTAVLDLRCLEPEGAAELRLDSHPCLEVTAAALRRERPGSEEPPAEPVSFYTQPFSHYGQALCVSFPQPCRAAERLQVLLTYRVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAVMSASTWEKRGPNKFFFQMCQPIPSYLIALAIGDLVSAEVGPRSRVWAEPCLIDAAKEEYNGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAATGRALLRQHMDITGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQDQFDSFLKAYVHEFKFRSILADDFLDFYLEYFPELKKKRVDIIPGFEFDRWLNTPGWPPYLPDLSPGDSLMKPAEELAQLWAAEELDMKAIEAVAISPWKTYQLVYFLDKILQKSPLPPGNVKKLGDTYPSISNARNAELRLRWGQIVLKNDHQEDFWKVKEFLHNQGKQKYTLPLYHAMMGGSEVAQTLAKETFASTASQLHSNVVNYVQQIVAPKGS
  
Inhibitor
Name:
BDBM50036829
Synonyms:
2-Mercapto-4-methylsulfanyl-butyric acid | CHEMBL27163
Type:
Small organic molecule
Emp. Form.:
C5H10O2S2
Mol. Mass.:
166.262
SMILES:
CSCCC(S)C(O)=O
Structure:
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