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Target
D(1A) dopamine receptor
Ligand
BDBM50029339
Substrate
n/a
Meas. Tech.
ChEMBL_58517 (CHEMBL672012)
Ki
75±n/a nM
Citation
 Shah, JH; Izenwasser, S; Geter-Douglass, B; Witkin, JM; Newman, AH (+/-)-(N-alkylamino)benzazepine analogs: novel dopamine D1 receptor antagonists. J Med Chem 38:4284-93 (1995) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49429.75
Organism:
RAT
Description:
P18901
Residue:
446
Sequence:
MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLEDTEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGSEETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPALSVILDYDTDVSLEKIQPVTHSGQHST
  
Inhibitor
Name:
BDBM50029339
Synonyms:
3-(4-Amino-butyl)-8-chloro-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol | CHEMBL133094
Type:
Small organic molecule
Emp. Form.:
C20H25ClN2O
Mol. Mass.:
344.878
SMILES:
NCCCCN1CCc2cc(Cl)c(O)cc2C(C1)c1ccccc1
Structure:
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