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Target
5-hydroxytryptamine receptor 1D
Ligand
BDBM50407737
Substrate
n/a
Meas. Tech.
ChEMBL_2007 (CHEMBL617302)
Ki
63±n/a nM
Citation
 Sonesson, C; Barf, T; Nilsson, J; Dijkstra, D; Carlsson, A; Svensson, K; Smith, MW; Martin, IJ; Duncan, JN; King, LJ Synthesis and evaluation of pharmacological and pharmacokinetic properties of monopropyl analogs of 5-, 7-, and 8-[[(trifluoromethyl)sulfonyl]oxy]-2-aminotetralins: central dopamine and serotonin receptor activity. J Med Chem 38:1319-29 (1995) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1D
Synonyms:
5-HT-1D | 5-HT-1D-alpha | 5-HT1D | 5-hydroxytryptamine receptor 1D (5-HT1D) | 5HT1D_HUMAN | HTR1D | HTR1DA | HTRL | Serotonin (5-HT) receptor | Serotonin Receptor 1D
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
41920.63
Organism:
Homo sapiens (Human)
Description:
Receptor binding assays were performed using human clone stably expressed in CHO cells.
Residue:
377
Sequence:
MSPLNQSAEGLPQEASNRSLNATETSEAWDPRTLQALKISLAVVLSVITLATVLSNAFVLTTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICISIPPLFWRQAKAQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNSSLHEGHSHSAGSPLFFNHVKIKLADSALERKRISAARERKATKILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKIVPFRKAS
  
Inhibitor
Name:
BDBM50407737
Synonyms:
CHEMBL2021538
Type:
Small organic molecule
Emp. Form.:
C15H20F3NO2S
Mol. Mass.:
335.385
SMILES:
CCCN[C@H]1CCc2c(CS(=O)(=O)C(F)(F)F)cccc2C1 |r|
Structure:
Search PDB for entries with ligand similarity: