Reaction Details Report a problem with these data
Target
Integrase
Ligand
BDBM50051626
Substrate
n/a
Meas. Tech.
ChEMBL_90733 (CHEMBL701285)
IC50
>100000±n/a nM
Citation
 Mazumder, A; Wang, S; Neamati, N; Nicklaus, M; Sunder, S; Chen, J; Milne, GW; Rice, WG; Burke, TR; Pommier, Y Antiretroviral agents as inhibitors of both human immunodeficiency virus type 1 integrase and protease. J Med Chem 39:2472-81 (1996) [PubMed]  Article 
Target
Name:
Integrase
Synonyms:
Human immunodeficiency virus type 1 integrase
Type:
PROTEIN
Mol. Mass.:
32231.48
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_90865
Residue:
288
Sequence:
FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSNFTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAKLLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
  
Inhibitor
Name:
BDBM50051626
Synonyms:
4-Hydroxy-7-methoxy-3-(toluene-4-sulfonyl)-chromen-2-one | CHEMBL310437 | NSC-619389
Type:
Small organic molecule
Emp. Form.:
C17H14O6S
Mol. Mass.:
346.354
SMILES:
COc1ccc2c(O)c(c(=O)oc2c1)S(=O)(=O)c1ccc(C)cc1
Structure:
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