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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM502
Substrate
n/a
Meas. Tech.
ChEMBL_159457 (CHEMBL766802)
IC50
750±n/a nM
Citation
 Mazumder, A; Wang, S; Neamati, N; Nicklaus, M; Sunder, S; Chen, J; Milne, GW; Rice, WG; Burke, TR; Pommier, Y Antiretroviral agents as inhibitors of both human immunodeficiency virus type 1 integrase and protease. J Med Chem 39:2472-81 (1996) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM502
Synonyms:
2-({4-[bis(3-hydroxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl)methyl]phenyl}(3-hydroxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl)methyl)-3-hydroxy-1,4-dihydronaphthalene-1,4-dione | CHEMBL66033 | Cancer Chemotherapy National Service Center (CCNSC) compound 117027 | NSC 117027
Type:
Small organic molecule
Emp. Form.:
C48H26O12
Mol. Mass.:
794.7128
SMILES:
Oc1c(O)c2ccccc2c(O)c1C(=C1C(=O)C(=O)c2ccccc2C1=O)c1ccc(cc1)C(C1C(=O)C(=O)c2ccccc2C1=O)C1C(=O)C(=O)c2ccccc2C1=O |w:13.14|
Structure:
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