Reaction Details Report a problem with these data
Target
Leukotriene B4 receptor 1
Ligand
BDBM50052021
Substrate
n/a
Meas. Tech.
ChEMBL_99851 (CHEMBL706922)
IC50
4±n/a nM
Citation
 Brooks, CD; Summers, JB Modulators of leukotriene biosynthesis and receptor activation. J Med Chem 39:2629-54 (1996) [PubMed]  Article 
Target
Name:
Leukotriene B4 receptor 1
Synonyms:
BLT | BLT1 | BLTR | CMKRL1 | Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | GPR16 | LT4R1_HUMAN | LTB4-R 1 | LTB4R | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2RY7 | P2Y purinoceptor 7 | P2Y7
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37582.68
Organism:
Homo sapiens (Human)
Description:
Q15722
Residue:
352
Sequence:
MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNLALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVARPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAFHLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVVNLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
  
Inhibitor
Name:
BDBM50052021
Synonyms:
4-[5-(4-Carbamimidoyl-phenoxy)-pentyloxy]-N,N-diisopropyl-3-methoxy-benzamide | CGS-250190 | CHEMBL89326
Type:
Small organic molecule
Emp. Form.:
C26H37N3O4
Mol. Mass.:
455.5897
SMILES:
COc1cc(ccc1OCCCCCOc1ccc(cc1)C(N)=N)C(=O)N(C(C)C)C(C)C
Structure:
Search PDB for entries with ligand similarity: