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TargetBeta-lactamase
LigandBDBM50053177
Substrate/Competitorn/a
Meas. Tech.ChEMBL_41030
IC50 1100±n/a nM
Citation Richter, HGAngehrn, PHubschwerlen, CKania, MPage, MGSpecklin, JLWinkler, FK Design, synthesis, and evaluation of 2 beta-alkenyl penam sulfone acids as inhibitors of beta-lactamases. J Med Chem39:3712-22 (1996) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Beta-lactamase
Name:Beta-lactamase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:41306.67
Organism:Enterobacter cloacae
Description:ChEMBL_40258
Residue:381
Sequence:
MMRKSLCCALLLGISCSALATPVSEKQLAEVVANTITPLMKAQSVPGMAVAVIYQGKPHY
YTFGKADIAANKPVTPQTLFELGSISKTFTGVLGGDAIARGEISLDDAVTRYWPQLTGKQ
WQGIRMLDLATYTAGGLPLQVPDEVTDNASLLRFYQNWQPQWKPGTTRLYANASIGLFGA
LAVKPSGMPYEQAMTTRVLKPLKLDHTWINVPKAEEAHYAWGYRDGKAVRVSPGMLDAQA
YGVKTNVQDMANWVMANMAPENVADASLKQGIALAQSRYWRIGSMYQGLGWEMLNWPVEA
NTVVEGSDSKVALAPLPVAEVNPPAPPVKASWVHKTGSTGGFGSYVAFIPEKQIGIVMLA
NTSYPNPARVEAAYHILEALQ
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50053177
NameBDBM50053177
Synonyms:(2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-((Z)-3-oxo-but-1-enyl)-4lambda*6*-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid | CHEMBL124960
TypeSmall organic molecule
Emp. Form.C11H13NO6S
Mol. Mass.287.289
SMILESCC(=O)C=C[C@@]1(C)[C@@H](N2[C@@H](CC2=O)S1(=O)=O)C(O)=O |w:3.2|
Structure
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n/a