Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetCoagulation factor X/antithrombin III
LigandBDBM50369254
Substrate/Competitorn/a
Meas. Tech.ChEMBL_35868
Kd 58±n/a nM
Citation Petitou, MDuchaussoy, PJaurand, GGourvenec, FLederman, IStrassel, JMBârzu, TCrépon, BHérault, JPLormeau, JCBernat, AHerbert, JM Synthesis and pharmacological properties of a close analogue of an antithrombotic pentasaccharide (SR 90107A/ORG 31540). J Med Chem40:1600-7 (1997) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Coagulation factor X/antithrombin III
Name:Coagulation factor X/antithrombin III
Synonyms:ATIII | Antithrombin-III | Antithrombin-III precursor
Type:PROTEIN
Mol. Mass.:52602.34
Organism:Homo sapiens
Description:ChEMBL_35871
Residue:464
Sequence:
MYSNVIGTVTSGKRKVYLLSLLLIGFWDCVTCHGSPVDICTAKPRDIPMNPMCIYRSPEK
KATEDEGSEQKIPEATNRRVWELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFA
MTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFG
DKSLTFNETYQDISELVYGAKLQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAIN
ELTVLVLVNTIYFKGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRVAEGTQ
VLELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDG
FSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAV
VIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANPCVK
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50369254
NameBDBM50369254
Synonyms:CHEMBL609990
TypeSmall organic molecule
Emp. Form.C30H41N3Na8O49S8
Mol. Mass.1668.076
SMILESOC1OC(COS(=O)(=O)O[Na])C(OC2OC(C(OC3OC(COS(=O)(=O)O[Na])C(OC4OC(C(OC5OC(COS(=O)(=O)O[Na])C(O)C(O)C5NS(=O)(=O)O[Na])C(O)C4O)C([O-])=O)C(OS(=O)(=O)O[Na])C3OS(=O)(=O)O[Na])C(O)C2NS(=O)(=O)O[Na])C([O-])=O)C(O)C1NS(=O)(=O)O[Na]
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a