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Target
Mu-type opioid receptor
Ligand
BDBM50060064
Substrate
n/a
Meas. Tech.
ChEMBL_147101 (CHEMBL758266)
IC50
>10000±n/a nM
Citation
 Salvadori, S; Balboni, G; Guerrini, R; Tomatis, R; Bianchi, C; Bryant, SD; Cooper, PS; Lazarus, LH Evolution of the Dmt-Tic pharmacophore: N-terminal methylated derivatives with extraordinary delta opioid antagonist activity. J Med Chem 40:3100-8 (1997) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50060064
Synonyms:
2-[(R)-2-Dimethylamino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid | CHEMBL318395
Type:
Small organic molecule
Emp. Form.:
C23H28N2O4
Mol. Mass.:
396.4794
SMILES:
CN(C)[C@H](Cc1c(C)cc(O)cc1C)C(=O)N1Cc2ccccc2CC1C(O)=O
Structure:
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