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TargetAdenosine receptor A1
LigandBDBM50267393
Substrate/Competitorn/a
Meas. Tech.ChEMBL_29005
Ki 9.5±n/a nM
Citation van der Wenden, EMCarnielli, MRoelen, HCLorenzen, Avon Frijtag Drabbe Künzel, JKIJzerman, AP 5'-substituted adenosine analogs as new high-affinity partial agonists for the adenosine A1 receptor. J Med Chem41:102-8 (1998) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Adenosine receptor A1
Name:Adenosine receptor
Synonyms:ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptors A1
Type:Protein
Mol. Mass.:36704.13
Organism:Rattus norvegicus (rat)
Description:n/a
Residue:326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
QRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFL
KIWNDHFRCQPKPPIDEDLPEEKAED
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50267393
NameBDBM50267393
Synonyms:CHEMBL477444 | N6-Cyclopentyl-9H-(5-chloro-5-deoxy-beta-D-ribofuranosyl)adenine
TypeSmall organic molecule
Emp. Form.C15H20ClN5O3
Mol. Mass.353.804
SMILESO[C@@H]1[C@@H](CCl)O[C@H]([C@@H]1O)n1cnc2c(NC3CCCC3)ncnc12 |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a