Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM50454904
Substrate
n/a
Meas. Tech.
ChEMBL_29987 (CHEMBL881273)
Ki
18800±n/a nM
Citation
 van der Wenden, EM; Carnielli, M; Roelen, HC; Lorenzen, A; von Frijtag Drabbe Künzel, JK; IJzerman, AP 5'-substituted adenosine analogs as new high-affinity partial agonists for the adenosine A1 receptor. J Med Chem 41:102-8 (1998) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
AA2AR_RAT | ADENOSINE A2a | Adenosine A2 receptor | Adenosine A2a receptor (A2a) | Adenosine Receptors A2a (A2a) | Adenosine receptor A2a and A3 | Adenosine receptors A2a | Adora2a | Rat striatal adenosine A2a receptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
45015.65
Organism:
Rattus norvegicus (rat)
Description:
Rat A2A receptors expressed in CHO cells.
Residue:
410
Sequence:
MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS
  
Inhibitor
Name:
BDBM50454904
Synonyms:
CHEMBL2113467
Type:
Small organic molecule
Emp. Form.:
C18H27N5O3S
Mol. Mass.:
393.504
SMILES:
CCCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC3CCCC3)ncnc12 |r|
Structure:
Search PDB for entries with ligand similarity: