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TargetBradykinin B2 receptor
LigandBDBM50067261
Substrate/Competitorn/a
Meas. Tech.ChEMBL_40264
IC50 3.8±n/a nM
Citation Abe, YKayakiri, HSatoh, SInoue, TSawada, YInamura, NAsano, MHatori, CSawai, HOku, TTanaka, H A novel class of orally active non-peptide bradykinin B2 receptor antagonists. 2. Overcoming the species difference between guinea pig and man. J Med Chem41:4053-61 (1998) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Bradykinin B2 receptor
Name:Bradykinin B2 receptor
Synonyms:n/a
Type:n/a
Mol. Mass.:42217.03
Organism:Cavia porcellus
Description:n/a
Residue:372
Sequence:
MFNITSQVSALNATLAQGNSCLDAEWWSWLNTIQAPFLWVLFVLAVLENIFVLSVFFLHK
SSCTVAEIYLGNLAVADLILAFGLPFWAITIANNFDWLFGEVLCRMVNTMIQMNMYSSIC
FLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWGCALLLSSPMLVFRTMKDYRDEGH
NVTACLIIYPSLTWQVFTNVLLNLVGFLLPLSIITFCTVQIMQVLRNNEMQKFKEIQTER
RATVLVLAVLLLFVVCWLPFQIGTFLDTLRLLGFLPGCWEHVIDLITQISSYLAYSNSCL
NPLVYVIVGKRFRKKSREVYHGLCRSGGCVSEPAQSENSMGTLRTSISVDRQIHKLQDWA
RSSSEGTPPGLL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50067261
NameBDBM50067261
Synonyms:CHEMBL556816 | N-[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4-dichloro-phenyl]-2-[3-(3-chloro-phenyl)-ureido]-N-methyl-acetamide; hydrochloride
TypeSmall organic molecule
Emp. Form.C25H21BrCl3N5O3
Mol. Mass.625.729
SMILESCN(C(=O)CNC(=O)Nc1cccc(Cl)c1)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl
Structure
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n/a