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Target
Lysosomal Pro-X carboxypeptidase
Ligand
BDBM83449
Substrate
n/a
Meas. Tech.
ChEMBL_154089 (CHEMBL760613)
IC50
91±n/a nM
Citation
 Moriarty, RM; Enache, LA; Zhao, L; Gilardi, R; Mattson, MV; Prakash, O Rigid phencyclidine analogues. Binding to the phencyclidine and sigma 1 receptors. J Med Chem 41:468-77 (1998) [PubMed]  Article 
Target
Name:
Lysosomal Pro-X carboxypeptidase
Synonyms:
Angiotensinase C | Lysosomal carboxypeptidase C | PCP | PCP_HUMAN | PRCP | Proline carboxypeptidase | Prolylcarboxypeptidase | Prolylcarboxypeptidase (PRCP)
Type:
Enzyme
Mol. Mass.:
55805.19
Organism:
Homo sapiens (Human)
Description:
P42785
Residue:
496
Sequence:
MGRRALLLLLLSFLAPWATIALRPALRALGSLHLPTNPTSLPAVAKNYSVLYFQQKVDHFGFNTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPHCSESIHRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSLEVRHMKNWIRDFYDSAGKQH
  
Inhibitor
Name:
BDBM83449
Synonyms:
1-(1-phenylcyclohexyl)piperidine;hydrochloride | MLS002320664 | PCP | PCP hydrochloride | PHENCYCLIDINE | Phencyclidine hydrochloride | SMR001338811 | cid_9795678
Type:
Small organic molecule
Emp. Form.:
C17H25N
Mol. Mass.:
243.3871
SMILES:
C1CCN(CC1)C1(CCCCC1)c1ccccc1
Structure:
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