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Target
Muscarinic acetylcholine receptor M5
Ligand
BDBM50073457
Substrate
n/a
Meas. Tech.
ChEMBL_139388 (CHEMBL747701)
IC50
167±n/a nM
Citation
 Augelli-Szafran, CE; Blankley, CJ; Jaen, JC; Moreland, DW; Nelson, CB; Penvose-Yi, JR; Schwarz, RD; Thomas, AJ Identification and characterization of m1 selective muscarinic receptor antagonists1. J Med Chem 42:356-63 (1999) [PubMed]  Article 
Target
Name:
Muscarinic acetylcholine receptor M5
Synonyms:
ACM5_HUMAN | CHRM5
Type:
PROTEIN
Mol. Mass.:
60102.35
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1517990
Residue:
532
Sequence:
MEGDSYHNATTVNGTPVNHQPLERHRLWEVITIAAVTAVVSLITIVGNVLVMISFKVNSQLKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGRWALGSLACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPKRAGIMIGLAWLISFILWAPAILCWQYLVGKRTVPLDECQIQFLSEPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQGSDSVTKAEKRKPAHRALFRSCLRCPRPTLAQRERNQASWSSSRRSTSTTGKPSQATGPSANWAKAEQLTTCSSYPSSEDEDKPATDPVLQVVYKSQGKESPGEEFSAEETEETFVKAETEKSDYDTPNYLLSPAAAHRPKSQKCVAYKFRLVVKADGNQETNNGCHKVKIMPCPFPVAKEPSTKGLNPNPSHQMTKRKRVVLVKERKAAQTLSAILLAFIITWTPYNIMVLVSTFCDKCVPVTLWHLGYWLCYVNSTVNPICYALCNRTFRKTFKMLLLCRWKKKKVEEKLYWQGNSKLP
  
Inhibitor
Name:
BDBM50073457
Synonyms:
(D,L) 1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid hexyl ester; compound with 2,3-dihydroxy-succinic acid | (R or S) 1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid hexyl ester; compound with 2,3-dihydroxy-succinic acid | CHEMBL333065
Type:
Small organic molecule
Emp. Form.:
C20H29NO2
Mol. Mass.:
315.4498
SMILES:
CCCCCCOC(=O)C1CN(CC)CC=C1c1ccccc1 |c:15|
Structure:
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