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Target
Ectonucleoside triphosphate diphosphohydrolase 1
Ligand
BDBM50369523
Substrate
n/a
Meas. Tech.
ChEMBL_143948 (CHEMBL751429)
Ki
31000±n/a nM
Citation
 Gendron, FP; Halbfinger, E; Fischer, B; Duval, M; D'Orléans-Juste, P; Beaudoin, AR Novel inhibitors of nucleoside triphosphate diphosphohydrolases: chemical synthesis and biochemical and pharmacological characterizations. J Med Chem 43:2239-47 (2000) [PubMed]  Article 
Target
Name:
Ectonucleoside triphosphate diphosphohydrolase 1
Synonyms:
ATPDase | CD39 | CD_antigen=CD39 | ENTP1_BOVIN | ENTPD1 | Ecto-ATP diphosphohydrolase | Ecto-apyrase | Lymphoid cell activation antigen | NTPDase 1
Type:
PROTEIN
Mol. Mass.:
58115.72
Organism:
Bos taurus
Description:
ChEMBL_143948
Residue:
513
Sequence:
MEDRRESELKVFCSKNILSILGFSCIIAVIALLALGLTQNKALPENVKFGIVLDAGSSHTSLYIYRWPAEKENDTGVVTQIEESNVKGPGISGFAKKVNEINVYLTACMERAQKVIPSIQHMETPVYLGATAGMRLLRMENKQMADKILAAVASSISEYPFDFQGARIISGQEEGAYGWITVNYLLGKFTQKLSWFNLKPSKDDTQETYGALDLGGASTQITFVPQNETTESPNNNLYFRLYGKNYSVYTHSFLCYGKDQALLQKLALGLQGTNGIIHEPCFHSRYMRKIKMSVLNEGFCTKRHELNSSFYPLVDIEIRGAGNFQRCRQSIIQLFNTSYCPYSSCSFNGVFLPPLHGQFGAFSAFYYVMEFLNLTSEESVSVEQLTEKLEEFCAQRWEEVQKNFGEVKEKYLSEYCFSGTYILVLLLNGYHFTAESWKNIHFMNKVRSTDVGWTLGYMLNLTNKIPAEEPMSPPLPHSTYVFLMVLFSLILLAVIIVGIVVFHKPSYFWKDMV
  
Inhibitor
Name:
BDBM50369523
Synonyms:
CHEMBL612159
Type:
Small organic molecule
Emp. Form.:
C17H28N5O13P3S
Mol. Mass.:
635.416
SMILES:
Nc1ncnc2n(C3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)c(SC3CCCCCC3)nc12 |r|
Structure:
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