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TargetAdenosine deaminase
LigandBDBM50288072
Substrate/Competitorn/a
Meas. Tech.ChEMBL_30800
Ki 3.74±n/a nM
Citation Pragnacharyulu, PVVarkhedkar, VCurtis, MAChang, IFAbushanab, E Adenosine deaminase inhibitors: synthesis and biological evaluation of unsaturated, aromatic, and oxo derivatives of (+)-erythro-9-(2'S-hydroxy-3'R-nonyl)adenine [(+)-EHNA]. J Med Chem43:4694-700 (2001) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Adenosine deaminase
Name:Adenosine deaminase
Synonyms:ADA | Adenosine aminohydrolase
Type:Enzyme
Mol. Mass.:40910.44
Organism:Bos taurus (bovine)
Description:n/a
Residue:363
Sequence:
MAQTPAFNKPKVELHVHLDGAIKPETILYYGRKRGIALPADTPEELQNIIGMDKPLSLPE
FLAKFDYYMPAIAGCREAVKRIAYEFVEMKAKDGVVYVEVRYSPHLLANSKVEPIPWNQA
EGDLTPDEVVSLVNQGLQEGERDFGVKVRSILCCMRHQPSWSSEVVELCKKYREQTVVAI
DLAGDETIEGSSLFPGHVKAYAEAVKSGVHRTVHAGEVGSANVVKEAVDTLKTERLGHGY
HTLEDATLYNRLRQENMHFEVCPWSSYLTGAWKPDTEHPVVRFKNDQVNYSLNTDDPLIF
KSTLDTDYQMTKNEMGFTEEEFKRLNINAAKSSFLPEDEKKELLDLLYKAYGMPSPASAE
QCL
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  Blast E-value cutoff:
BDBM50288072
NameBDBM50288072
Synonyms:(Z)-(2S,3R)-3-(6-Amino-purin-9-yl)-non-5-en-2-ol | 3-(6-Amino-purin-9-yl)-non-5-en-2-ol | CHEMBL81390
TypeSmall organic molecule
Emp. Form.C14H21N5O
Mol. Mass.275.3494
SMILESCCC\C=C/C[C@H]([C@H](C)O)n1cnc2c(N)ncnc12
Structure
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n/a