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Target
P2Y purinoceptor 1
Ligand
BDBM50085822
Substrate
n/a
Meas. Tech.
ChEMBL_222620 (CHEMBL846295)
IC50
40000±n/a nM
Citation
 Nandanan, E; Jang, SY; Moro, S; Kim, HO; Siddiqui, MA; Russ, P; Marquez, VE; Busson, R; Herdewijn, P; Harden, TK; Boyer, JL; Jacobson, KA Synthesis, biological activity, and molecular modeling of ribose-modified deoxyadenosine bisphosphate analogues as P2Y(1) receptor ligands. J Med Chem 43:829-42 (2000) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 1
Synonyms:
P2RY1 | P2RY1_MELGA
Type:
n/a
Mol. Mass.:
41199.64
Organism:
Meleagris gallopavo
Description:
n/a
Residue:
362
Sequence:
MTEALISAALNGTQPELLAGGWAAGNASTKCSLTKTGFQFYYLPTVYILVFITGFLGNSVAIWMFVFHMRPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDVMCKLQRFIFHVNLYGSILFLTCISVHRYTGVVHPLKSLGRLKKKNAVYVSSLVWALVVAVIAPILFYSGTGVRRNKTITCYDTTADEYLRSYFVYSMCTTVFMFCIPFIVILGCYGLIVKALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYLPFHVMKTLNLRARLDFQTPQMCAFNDKVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKSSRRSEPNVQSKSEEMTLNILTEYKQNGDTSL
  
Inhibitor
Name:
BDBM50085822
Synonyms:
CHEMBL444868 | Phosphoric acid mono-[1-(6-amino-purin-9-yl)-4-phosphonooxymethyl-bicyclo[3.1.0]hex-3-yl] ester
Type:
Small organic molecule
Emp. Form.:
C12H17N5O8P2
Mol. Mass.:
421.2396
SMILES:
Nc1ncnc2n(cnc12)C12CC1C(COP(O)(O)=O)C(C2)OP(O)(O)=O
Structure:
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