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Target
Corticotropin-releasing factor receptor 2
Ligand
BDBM50087703
Substrate
n/a
Meas. Tech.
ChEMBL_220717 (CHEMBL843662)
EC50
0.32±n/a nM
Citation
 Gilligan, PJ; Robertson, DW; Zaczek, R Corticotropin releasing factor (CRF) receptor modulators: progress and opportunities for new therapeutic agents. J Med Chem 43:1641-60 (2000) [PubMed]  Article 
Target
Name:
Corticotropin-releasing factor receptor 2
Synonyms:
CRF-R 2 | CRF2 | CRF2R | CRFR2_HUMAN | CRH-R 2 | CRH2R | CRHR2 | Corticotropin releasing factor receptor 2 | Corticotropin-releasing factor receptor 2 (CRF-2) | Corticotropin-releasing factor receptor 2/Corticotropin-releasing factor-binding protein | Corticotropin-releasing hormone receptor 2
Type:
Enzyme
Mol. Mass.:
47694.70
Organism:
Homo sapiens (Human)
Description:
Q13324
Residue:
411
Sequence:
MDAALLHSLLEANCSLALAEELLLDGWGPPLDPEGPYSYCNTTLDQIGTCWPRSAAGALVERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCEPILDDKQRKYDLHYRIALVVNYLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTFILRNVMWFLLQLVDHEVHESNEVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIVAWAIGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYCFFNGEVRSAVRKRWHRWQDHHSLRVPMARAMSIPTSPTRISFHSIKQTAAV
  
Inhibitor
Name:
BDBM50087703
Synonyms:
CHEMBL427807 | Urocortin-human(DNPSLSIDLTFHLLRTLLELARTQSQRERAEQNRIIFDSV-NH2) | analogue of human corticotropin-releasing factor (hCRF)
Type:
Small organic molecule
Emp. Form.:
C204H337N63O64
Mol. Mass.:
4696.2423
SMILES:
n/a
Structure:
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