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Target
Adenosine receptor A1
Ligand
BDBM50102284
Substrate
n/a
Meas. Tech.
ChEMBL_29134 (CHEMBL637556)
Ki
184±n/a nM
Citation
 Da Settimo, F; Primofiore, G; Taliani, S; Marini, AM; La Motta, C; Novellino, E; Greco, G; Lavecchia, A; Trincavelli, L; Martini, C 3-Aryl[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-ones: a new class of selective A1 adenosine receptor antagonists. J Med Chem 44:316-27 (2001) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_BOVIN | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36602.99
Organism:
BOVINE
Description:
ADENOSINE 0 BOVINE::P28190
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPRTYFHTCLKVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAVVAITGCWILSFVVGLTPMFGWNNLSAVERDWLANGSVGEPVIECQFEKVISMEYMVYFNFFVWVLPPLLLMVLIYMEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHMPRILIYIAIFLSHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPVDEDAPAERPDD
  
Inhibitor
Name:
BDBM50102284
Synonyms:
10-Benzyl-3-phenyl-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-4-one | CHEMBL326752
Type:
Small organic molecule
Emp. Form.:
C22H16N4O
Mol. Mass.:
352.3886
SMILES:
O=c1c(nnc2n(Cc3ccccc3)c3ccccc3n12)-c1ccccc1
Structure:
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