Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50097440
Substrate
n/a
Meas. Tech.
ChEMBL_32009 (CHEMBL646606)
Ki
410±n/a nM
Citation
 van Muijlwijk-Koezen, JE; Timmerman, H; Vollinga, RC; Frijtag von Drabbe Künzel, J; de Groote, M; Visser, S; IJzerman, AP Thiazole and thiadiazole analogues as a novel class of adenosine receptor antagonists. J Med Chem 44:749-62 (2001) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50097440
Synonyms:
CHEMBL165783 | N-(3-Phenyl-[1,2,4]thiadiazol-5-yl)-benzamide
Type:
Small organic molecule
Emp. Form.:
C15H11N3OS
Mol. Mass.:
281.332
SMILES:
O=C(Nc1nc(ns1)-c1ccccc1)c1ccccc1
Structure:
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