Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetPyrimidinergic receptor P2Y4
LigandBDBM50306712
Substrate/Competitorn/a
Meas. Tech.ChEMBL_147872
EC50 49±n/a nM
Citation Kim, HSRavi, RGMarquez, VEMaddileti, SWihlborg, AKErlinge, DMalmsjö, MBoyer, JLHarden, TKJacobson, KA Methanocarba modification of uracil and adenine nucleotides: high potency of Northern ring conformation at P2Y1, P2Y2, P2Y4, and P2Y11 but not P2Y6 receptors. J Med Chem45:208-18 (2001) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Pyrimidinergic receptor P2Y4
Name:Pyrimidinergic receptor P2Y4
Synonyms:P2P | P2Y purinoceptor 4 | P2Y4 | UNR | Uridine nucleotide receptor
Type:PROTEIN
Mol. Mass.:40977.17
Organism:Homo sapiens (Human)
Description:ChEMBL_751027
Residue:365
Sequence:
MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLF
IFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLY
CSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKG
TTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSR
LRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSC
LDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTP
RADRL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50306712
NameBDBM50306712
Synonyms:((1R,2R,3S,4R,5S)-4-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,3-dihydroxybicyclo[3.1.0]hexan-1-yl)methyl tetrahydrogen triphosphate | CHEMBL606210
TypeSmall organic molecule
Emp. Form.C11H17N2O14P3
Mol. Mass.494.179
SMILESO[C@@H]1[C@H](O)[C@]2(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C[C@@H]2[C@H]1n1ccc(=O)[nH]c1=O |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a