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TargetPurinergic receptor P2Y11
LigandBDBM50409486
Substrate/Competitorn/a
Meas. Tech.ChEMBL_147735
EC50 17250±n/a nM
Citation Kim, HSRavi, RGMarquez, VEMaddileti, SWihlborg, AKErlinge, DMalmsjö, MBoyer, JLHarden, TKJacobson, KA Methanocarba modification of uracil and adenine nucleotides: high potency of Northern ring conformation at P2Y1, P2Y2, P2Y4, and P2Y11 but not P2Y6 receptors. J Med Chem45:208-18 (2001) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Purinergic receptor P2Y11
Name:Purinergic receptor P2Y11
Synonyms:P2Y purinoceptor 11 | P2Y11
Type:PROTEIN
Mol. Mass.:40366.02
Organism:Homo sapiens (Human)
Description:ChEMBL_1362532
Residue:374
Sequence:
MAANVSGAKSCPANFLAAADDKLSGFQGDFLWPILVVEFLVAVASNGLALYRFSIRKQRP
WHPAVVFSVQLAVSDLLCALTLPPLAAYLYPPKHWRYGEAACRLERFLFTCNLLGSVIFI
TCISLNRYLGIVHPFFARSHLRPKHAWAVSAAGWVLAALLAMPTLSFSHLKRPQQGAGNC
SVARPEACIKCLGTADHGLAAYRAYSLVLAGLGCGLPLLLTLAAYGALGRAVLRSPGMTV
AEKLRVAALVASGVALYASSYVPYHIMRVLNVDARRRWSTRCPSFADIAQATAALELGPY
VGYQVMRGLMPLAFCVHPLLYMAAVPSLGCCCRHCPGYRDSWNPEDAKSTGQALPLNATA
APKPSEPQSRELSQ
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50409486
NameBDBM50409486
Synonyms:CHEMBL2111533
TypeSmall organic molecule
Emp. Form.C12H18N5O12P3
Mol. Mass.517.2189
SMILESNc1ncnc2n(cnc12)[C@@H]1[C@H]2C[C@@]2(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O
Structure
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