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Target
P2Y purinoceptor 1
Ligand
BDBM50409525
Substrate
n/a
Meas. Tech.
ChEMBL_162517 (CHEMBL766763)
EC50
3900±n/a nM
Citation
 Ravi, RG; Kim, HS; Servos, J; Zimmermann, H; Lee, K; Maddileti, S; Boyer, JL; Harden, TK; Jacobson, KA Adenine nucleotide analogues locked in a Northern methanocarba conformation: enhanced stability and potency as P2Y(1) receptor agonists. J Med Chem 45:2090-100 (2002) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 1
Synonyms:
P2RY1 | P2RY1_MELGA
Type:
n/a
Mol. Mass.:
41199.64
Organism:
Meleagris gallopavo
Description:
n/a
Residue:
362
Sequence:
MTEALISAALNGTQPELLAGGWAAGNASTKCSLTKTGFQFYYLPTVYILVFITGFLGNSVAIWMFVFHMRPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDVMCKLQRFIFHVNLYGSILFLTCISVHRYTGVVHPLKSLGRLKKKNAVYVSSLVWALVVAVIAPILFYSGTGVRRNKTITCYDTTADEYLRSYFVYSMCTTVFMFCIPFIVILGCYGLIVKALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYLPFHVMKTLNLRARLDFQTPQMCAFNDKVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKSSRRSEPNVQSKSEEMTLNILTEYKQNGDTSL
  
Inhibitor
Name:
BDBM50409525
Synonyms:
CHEMBL2112090
Type:
Small organic molecule
Emp. Form.:
C12H15ClN5O6P
Mol. Mass.:
391.704
SMILES:
Nc1nc(Cl)nc2n(cnc12)[C@@H]1[C@H]2C[C@@]2(COP(O)(O)=O)[C@@H](O)[C@H]1O
Structure:
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