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Target
Melanocortin receptor 4
Ligand
BDBM50114750
Substrate
n/a
Meas. Tech.
ChEMBL_104252 (CHEMBL714370)
EC50
1500±n/a nM
Citation
 Holder, JR; Bauzo, RM; Xiang, Z; Haskell-Luevano, C Structure-activity relationships of the melanocortin tetrapeptide Ac-His-DPhe-Arg-Trp-NH(2) at the mouse melanocortin receptors. 1. Modifications at the His position. J Med Chem 45:2801-10 (2002) [PubMed]  Article 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R_MOUSE | Mc4r
Type:
PROTEIN
Mol. Mass.:
36964.43
Organism:
Mus musculus
Description:
ChEMBL_1498850
Residue:
332
Sequence:
MNSTHHHGMYTSLHLWNRSSYGLHGNASESLGKGHPDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVRRVGIIISCIWAACTVSGVLFIIYSDSSAVIICLISMFFTMLVLMASLYVHMFLMARLHIKRIAVLPGTGTIRQGTNMKGAITLTILIGVFVVCWAPFFLHLLFYISCPQNPYCVCFMSHFNLYLILIMCNAVIDPLIYALRSQELRKTFKEIICFYPLGGICELSSRY
  
Inhibitor
Name:
BDBM50114750
Synonyms:
3-{2-[1-[1-[1-acetyl-(5S)-dihydro-1H-5-pyrrolylcarboxamido]-2-phenyl-(1R)-ethylcarboxamido]-4-amino(imino)methylamino-(1S)-butylcarboxamido]-2-carbamoylethyl}-1H-indole | CHEMBL320157
Type:
Small organic molecule
Emp. Form.:
C33H43N9O5
Mol. Mass.:
645.7518
SMILES:
CC(=O)N1CCC[C@H]1C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Structure:
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