Reaction Details Report a problem with these data
Target
P2X purinoceptor 2
Ligand
BDBM85043
Substrate
n/a
Meas. Tech.
ChEMBL_147392 (CHEMBL751112)
EC50
12000±n/a nM
Citation
 Jacobson, KA; Jarvis, MF; Williams, M Purine and pyrimidine (P2) receptors as drug targets. J Med Chem 45:4057-93 (2002) [PubMed]  Article 
Target
Name:
P2X purinoceptor 2
Synonyms:
ATP receptor | P2RX2_RAT | P2X purinoceptor 2 | P2X2 | P2X2/P2X3 receptor | P2rx2 | Purinergic receptor | Purinergic, P2X2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52625.55
Organism:
RAT
Description:
Purinergic, P2X2 0 RAT::P49653
Residue:
472
Sequence:
MVRRLARGCWSAFWDYETPKVIVVRNRRLGFVHRMVQLLILLYFVWYVFIVQKSYQDSETGPESSIITKVKGITMSEDKVWDVEEYVKPPEGGSVVSIITRIEVTPSQTLGTCPESMRVHSSTCHSDDDCIAGQLDMQGNGIRTGHCVPYYHGDSKTCEVSAWCPVEDGTSDNHFLGKMAPNFTILIKNSIHYPKFKFSKGNIASQKSDYLKHCTFDQDSDPYCPIFRLGFIVEKAGENFTELAHKGGVIGVIINWNCDLDLSESECNPKYSFRRLDPKYDPASSGYNFRFAKYYKINGTTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSIGVGSFLCDWILLTFMNKNKLYSHKKFDKVRTPKHPSSRWPVTLALVLGQIPPPPSHYSQDQPPSPPSGEGPTLGEGAELPLAVQSPRPCSISALTEQVVDTLGQHMGQRPPVPEPSQQDSTSTDPKGLAQL
  
Inhibitor
Name:
BDBM85043
Synonyms:
CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPADS
Type:
Small organic molecule
Emp. Form.:
C14H14N3O12PS2
Mol. Mass.:
511.378
SMILES:
Cc1nc(N=Nc2ccc(cc2S(O)(=O)=O)S(O)(=O)=O)c(COP(O)(O)=O)c(C=O)c1O |w:4.3|
Structure:
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