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Target
P2X purinoceptor 6
Ligand
BDBM50118221
Substrate
n/a
Meas. Tech.
ChEMBL_147419 (CHEMBL750993)
EC50
>8000±n/a nM
Citation
 Jacobson, KA; Jarvis, MF; Williams, M Purine and pyrimidine (P2) receptors as drug targets. J Med Chem 45:4057-93 (2002) [PubMed]  Article 
Target
Name:
P2X purinoceptor 6
Synonyms:
ATP receptor | P2RX6_RAT | P2X6 | P2XM | P2rx6 | P2rxl1 | Purinergic receptor | Purinergic receptor P2X-like 1
Type:
PROTEIN
Mol. Mass.:
42451.11
Organism:
Rattus norvegicus
Description:
ChEMBL_147419
Residue:
379
Sequence:
MASAVAAALVSWGFLDYKTEKYVMTRNCWVGISQRLLQLGVVVYVIGWALLAKKGYQEWDMDPQISVITKLKGVSVTQVKELEKRLWDVADFVRPSQGENVFFLVTNFLVTPAQVQGRCPEHPSVPLANCWADEDCPEGEMGTYSHGIKTGQCVAFNGTHRTCEIWSWCPVESSAVPRKPLLAQAKNFTLFIKNTVTFNKFNFSRTNALDTWDNTYFKYCLYDSLSSPYCPVFRIGDLVAMTGGDFEDLALLGGAVGINIHWDCNLDTKGSDCSPQYSFQLQERGYNFRTANYWWAASGVESRSLLKLYGIRFDILVTGQAGKFALIPTAITVGTGAAWLGMVTFLCDLLLLYVDREAGFYWRTKYEEARAPKATTNSA
  
Inhibitor
Name:
BDBM50118221
Synonyms:
9H-purine derivative | CHEMBL132722 | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER | alpha,beta-meATP
Type:
Small organic molecule
Emp. Form.:
C11H18N5O12P3
Mol. Mass.:
505.2082
SMILES:
Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)CP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O
Structure:
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