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Target
D(2) dopamine receptor
Ligand
BDBM50108710
Substrate
n/a
Meas. Tech.
ChEMBL_87873 (CHEMBL697295)
Ki
1100±n/a nM
Citation
 Fletcher, SR; Burkamp, F; Blurton, P; Cheng, SK; Clarkson, R; O'Connor, D; Spinks, D; Tudge, M; van Niel, MB; Patel, S; Chapman, K; Marwood, R; Shepheard, S; Bentley, G; Cook, GP; Bristow, LJ; Castro, JL; Hutson, PH; MacLeod, AM 4-(Phenylsulfonyl)piperidines: novel, selective, and bioavailable 5-HT(2A) receptor antagonists. J Med Chem 45:492-503 (2002) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50108710
Synonyms:
4-(4-Benzenesulfonyl-piperidin-1-yl)-1-(4-fluoro-phenyl)-butan-1-one | CHEMBL343411
Type:
Small organic molecule
Emp. Form.:
C21H24FNO3S
Mol. Mass.:
389.484
SMILES:
Fc1ccc(cc1)C(=O)CCCN1CCC(CC1)S(=O)(=O)c1ccccc1
Structure:
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