Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetAdenosine receptor A3
LigandBDBM50118799
Substrate/Competitorn/a
Meas. Tech.ChEMBL_31394
EC50 1.4±n/a nM
Citation Gao, ZGKim, SKBiadatti, TChen, WLee, KBarak, DKim, SGJohnson, CRJacobson, KA Structural determinants of A(3) adenosine receptor activation: nucleoside ligands at the agonist/antagonist boundary. J Med Chem45:4471-84 (2002) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Adenosine receptor A3
Name:Adenosine receptors; A2b & A3
Synonyms:A3 adenosine receptor (hA3) | Adenosine A3 receptor (A3AR)
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:36197.32
Organism:Homo sapiens (human)
Description:Human A3 receptors expressed in CHO cells.
Residue:318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50118799
NameBDBM50118799
Synonyms:4-(2-Chloro-6-methylamino-purin-9-yl)-2,3-dihydroxy-bicyclo[3.1.0]hexane-1-carboxylic acid methylamide | CHEMBL345076
TypeSmall organic molecule
Emp. Form.C14H17ClN6O3
Mol. Mass.352.776
SMILESCNC(=O)C12CC1C(C(O)C2O)n1cnc2c(NC)nc(Cl)nc12
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a