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TargetDopamine receptor D2L/neurotensin receptor NTS1
LigandBDBM50130890
Substrate/Competitorn/a
Meas. Tech.ChEMBL_144289
IC50 6.3±n/a nM
Citation Achilefu, SSrinivasan, ASchmidt, MAJimenez, HNBugaj, JEErion, JL Novel bioactive and stable neurotensin peptide analogues capable of delivering radiopharmaceuticals and molecular beacons to tumors. J Med Chem46:3403-11 (2003) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Dopamine receptor D2L/neurotensin receptor NTS1
Name:Dopamine receptor D2L/neurotensin receptor NTS1
Synonyms:Neurotensin receptor 1 | neurotensin receptor type 1
Type:PROTEIN
Mol. Mass.:46278.89
Organism:Homo sapiens (Human)
Description:ChEMBL_1453811
Residue:418
Sequence:
MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDI
YSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAM
PVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLM
SRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVN
TFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRH
GVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTIN
PILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
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  Blast E-value cutoff:
BDBM50130890
NameBDBM50130890
Synonyms:CHEMBL413192 | DTPA-DLys-Pro-Arg-hAla(PipAm)-Arg-Pro-Tyr-tBuGly-Leu-OH
TypeSmall organic molecule
Emp. Form.C67H110N18O19
Mol. Mass.1471.6995
SMILESCC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC1CCN(CC1)C(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](CCCCN)NC(=O)CN(CCN(CCN(CC(O)=O)CC(O)=O)CC(O)=O)CC(O)=O)C(C)(C)C)C(O)=O
Structure
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