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Target
Thymidine kinase, cytosolic
Ligand
BDBM50135089
Substrate
n/a
Meas. Tech.
ChEMBL_208002 (CHEMBL816084)
Ki
220±n/a nM
Citation
 Russ, P; Schelling, P; Scapozza, L; Folkers, G; Clercq, ED; Marquez, VE Synthesis and biological evaluation of 5-substituted derivatives of the potent antiherpes agent (north)-methanocarbathymine. J Med Chem 46:5045-54 (2003) [PubMed]  Article 
Target
Name:
Thymidine kinase, cytosolic
Synonyms:
KITH_HUMAN | TK1
Type:
PROTEIN
Mol. Mass.:
25476.50
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1333884
Residue:
234
Sequence:
MSCINLPTVLPGSPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTRYSSSFCTHDRNTMEALPACLLRDVAQEALGVAVIGIDEGQFFPDIVEFCEAMANAGKTVIVAALDGTFQRKPFGAILNLVPLAESVVKLTAVCMECFREAAYTKRLGTEKEVEVIGGADKYHSVCRLCYFKKASGQPAGPDNKENCPVPGKPGEAVAARKLFAPQQILQCSPAN
  
Inhibitor
Name:
BDBM50135089
Synonyms:
C-BVdU | CHEMBL341644
Type:
Small organic molecule
Emp. Form.:
C12H15BrN2O4
Mol. Mass.:
331.162
SMILES:
OC[C@@H]1C[C@@H](C[C@H]1O)n1cc(C=CBr)c(=O)[nH]c1=O |w:12.13|
Structure:
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