Reaction Details Report a problem with these data
Target
Carbonic anhydrase
Ligand
BDBM26994
Substrate
n/a
Meas. Tech.
ChEMBL_302701 (CHEMBL876781)
Ki
9600000±n/a nM
Citation
 Innocenti, A; Zimmerman, S; Ferry, JG; Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors. Inhibition of the beta-class enzyme from the methanoarchaeon Methanobacterium thermoautotrophicum (Cab) with anions. Bioorg Med Chem Lett 14:4563-7 (2004) [PubMed]  Article 
Target
Name:
Carbonic anhydrase
Synonyms:
CAH_METTT | CAM | Carbonic anhydrase | Gamma-carbonic anhydrase
Type:
Protein
Mol. Mass.:
26390.56
Organism:
Methanosarcina thermophila
Description:
P40881
Residue:
247
Sequence:
MMFNKQIFTILILSLSLALAGSGCISEGAEDNVAQEITVDEFSNIRENPVTPWNPEPSAPVIDPTAYIDPQASVIGEVTIGANVMVSPMASIRSDEGMPIFVGDRSNVQDGVVLHALETINEEGEPIEDNIVEVDGKEYAVYIGNNVSLAHQSQVHGPAAVGDDTFIGMQAFVFKSKVGNNCVLEPRSAAIGVTIPDGRYIPAGMVVTSQAEADKLPEVTDDYAYSHTNEAVVYVNVHLAEGYKETS
  
Inhibitor
Name:
BDBM26994
Synonyms:
CHEMBL68253 | H2NSO3H | sulfamic acid
Type:
n/a
Emp. Form.:
H3NO3S
Mol. Mass.:
97.094
SMILES:
NS(O)(=O)=O
Structure:
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