Reaction Details Report a problem with these data
Target
Adenosylhomocysteinase
Ligand
BDBM50370430
Substrate
n/a
Meas. Tech.
ChEMBL_302332 (CHEMBL828918)
Ki
75000±n/a nM
Citation
 Guillerm, G; Muzard, M; Glapski, C Inactivation of S-adenosylhomocysteine hydrolase with haloethyl and dihalocyclopropyl esters derived from homoadenosine-6'-carboxylic acid. Bioorg Med Chem Lett 14:5799-802 (2004) [PubMed]  Article 
Target
Name:
Adenosylhomocysteinase
Synonyms:
AHCY | Adenosylhomocysteinase | SAHH | SAHH_HUMAN
Type:
PROTEIN
Mol. Mass.:
47714.06
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1507791
Residue:
432
Sequence:
MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY
  
Inhibitor
Name:
BDBM50370430
Synonyms:
CHEMBL610300
Type:
Small organic molecule
Emp. Form.:
C13H16FN5O5
Mol. Mass.:
341.295
SMILES:
Nc1ncnc2n(cnc12)C1O[C@H](CC(=O)OCCF)[C@@H](O)[C@H]1O |r|
Structure:
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