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Target5-Hydroxytryptamine receptor 6 (5-HT6)
LigandBDBM50169600
Substrate/Competitorn/a
Meas. Tech.ChEMBL_302678
Ki 640±n/a nM
Citation Abate, CKolanos, RDukat, MSetola, VRoth, BLGlennon, RA Interaction of chiral MS-245 analogs at h5-HT6 receptors. Bioorg Med Chem Lett15:3510-3 (2005) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
5-Hydroxytryptamine receptor 6 (5-HT6)
Name:Serotonin (5-HT) receptor
Synonyms:5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:46968.43
Organism:Homo sapiens (Human)
Description:Cultured Hela cells expressing h5-HT6 receptors.
Residue:440
Sequence:
MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
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  Blast E-value cutoff:
BDBM50169600
NameBDBM50169600
Synonyms:3-((R)-1-Methyl-pyrrolidin-2-ylmethyl)-1H-indole; hydrochloride | CHEMBL539327
TypeSmall organic molecule
Emp. Form.C14H18N2
Mol. Mass.214.3061
SMILESCN1CCC[C@@H]1Cc1c[nH]c2ccccc12
Structure
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