Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50150763
Substrate
n/a
Meas. Tech.
ChEMBL_303370 (CHEMBL839688)
Ki
288±n/a nM
Citation
 Bosch, MP; Campos, F; Niubó, I; Rosell, G; Díaz, JL; Brea, J; Loza, MI; Guerrero, A Synthesis and biological activity of new potential agonists for the human adenosine A2A receptor. J Med Chem 47:4041-53 (2004) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50150763
Synonyms:
(2R,3R,4S,5R)-2-{6-Amino-2-[(S)-2-(4-chloro-phenyl)-1-hydroxymethyl-ethylamino]-purin-9-yl}-5-(2-ethyl-2H-tetrazol-5-yl)-tetrahydro-furan-3,4-diol | CHEMBL360646
Type:
Small organic molecule
Emp. Form.:
C21H25ClN10O4
Mol. Mass.:
516.941
SMILES:
CCn1nnc(n1)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(N[C@H](CO)Cc3ccc(Cl)cc3)nc12
Structure:
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