Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50156142
Substrate
n/a
Meas. Tech.
ChEMBL_302137 (CHEMBL841761)
Kd
3.04±n/a nM
Citation
 Shuman, CFVrang, LDanielson, UH Improved structure-activity relationship analysis of HIV-1 protease inhibitors using interaction kinetic data. J Med Chem 47:5953-61 (2004) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50156142
Synonyms:
1,6-Bis-(2,3-dimethyl-butyrylamino)-3,4-dihydroxy-1,6-dioxo-5-[4-(2H-1lambda*4*-thiophen-3-yl)-phenoxy]-hexan-2-ol anion | CHEMBL365756
Type:
Small organic molecule
Emp. Form.:
C28H38N2O8S
Mol. Mass.:
562.675
SMILES:
CC(C)[C@H](C)C(=O)NC(=O)[C@H]([O-])[C@H](O)[C@@H](O)[C@@H](Oc1ccc(cc1)C1=CC=[S+]C1)C(=O)NC(=O)[C@@H](C)C(C)C |c:27,t:25|
Structure:
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