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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM346
Substrate
n/a
Meas. Tech.
ChEMBL_302137 (CHEMBL841761)
Kd
39.8±n/a nM
Citation
 Shuman, CF; Vrang, L; Danielson, UH Improved structure-activity relationship analysis of HIV-1 protease inhibitors using interaction kinetic data. J Med Chem 47:5953-61 (2004) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM346
Synonyms:
(3R,4S,5S,6R)-4,5-dihydroxy-2,7-bis({[4-(hydroxymethyl)phenyl]methyl})-3,6-bis(phenoxymethyl)-1,2,7-thiadiazepane-1,1-dione | CHEMBL340616 | Cyclic Sulfamide deriv. 24
Type:
Small organic molecule
Emp. Form.:
C34H38N2O8S
Mol. Mass.:
634.739
SMILES:
OCc1ccc(CN2[C@H](COc3ccccc3)[C@H](O)[C@@H](O)[C@@H](COc3ccccc3)N(Cc3ccc(CO)cc3)S2(=O)=O)cc1 |r|
Structure:
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