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TargetEquilibrative Nucleoside Transporter 1 (ENT1)
LigandBDBM50370558
Substrate/Competitorn/a
Meas. Tech.ChEMBL_303651
Ki 410±n/a nM
Citation Tromp, RASpanjersberg, RFvon Frijtag Drabbe Künzel, JKIJzerman, AP Inhibition of nucleoside transport proteins by C8-alkylamine-substituted purines. J Med Chem48:321-9 (2005) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Equilibrative Nucleoside Transporter 1 (ENT1)
Name:Equilibrative nucleoside transporter 1
Synonyms:ENT1 | Equilibrative NBMPR-sensitive nucleoside transporter | Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter | Nucleoside transporter, es-type | Solute carrier family 29 member 1
Type:Multi-pass membrane protein
Mol. Mass.:50225.92
Organism:Homo sapiens (Human)
Description:n/a
Residue:456
Sequence:
MTTSHQPQDRYKAVWLIFFMLGLGTLLPWNFFMTATQYFTNRLDMSQNVSLVTAELSKDA
QASAAPAAPLPERNSLSAIFNNVMTLCAMLPLLLFTYLNSFLHQRIPQSVRILGSLVAIL
LVFLITAILVKVQLDALPFFVITMIKIVLINSFGAILQGSLFGLAGLLPASYTAPIMSGQ
GLAGFFASVAMICAIASGSELSESAFGYFITACAVIILTIICYLGLPRLEFYRYYQQLKL
EGPGEQETKLDLISKGEEPRAGKEESGVSVSNSQPTNESHSIKAILKNISVLAFSVCFIF
TITIGMFPAVTVEVKSSIAGSSTWERYFIPVSCFLTFNIFDWLGRSLTAVFMWPGKDSRW
LPSLVLARLVFVPLLLLCNIKPRRYLTVVFEHDAWFIFFMAAFAFSNGYLASLCMCFGPK
KVKPAEAETAGAIMAFFLCLGLALGAVFSFLFRAIV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50370558
NameBDBM50370558
Synonyms:CHEMBL609376
TypeSmall organic molecule
Emp. Form.C21H25N5O4S
Mol. Mass.443.519
SMILESOC[C@H]1OC([C@H](O)[C@@H]1O)n1c(nc2c(SCc3ccccc3)ncnc12)N1CCCC1 |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a