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Target
Peroxisomal primary amine oxidase
Ligand
BDBM50161135
Substrate
n/a
Meas. Tech.
ChEMBL_306749 (CHEMBL830894)
IC50
53000±n/a nM
Citation
 Bertini, V; Buffoni, F; Ignesti, G; Picci, N; Trombino, S; Iemma, F; Alfei, S; Pocci, M; Lucchesini, F; De Munno, A Alkylamino derivatives of 4-aminomethylpyridine as inhibitors of copper-containing amine oxidases. J Med Chem 48:664-70 (2005) [PubMed]  Article 
Target
Name:
Peroxisomal primary amine oxidase
Synonyms:
AMO | AMO_PICAN | Amine oxidase, copper containing
Type:
PROTEIN
Mol. Mass.:
77535.84
Organism:
Pichia angusta
Description:
ChEMBL_306687
Residue:
692
Sequence:
MERLRQIASQATAASAAPARPAHPLDPLSTAEIKAATNTVKSYFAGKKISFNTVTLREPARKAYIQWKEQGGPLPPRLAYYVILEAGKPGVKEGLVDLASLSVIETRALETVQPILTVEDLCSTEEVIRNDPAVIEQCVLSGIPANEMHKVYCDPWTIGYDERWGTGKRLQQALVYYRSDEDDSQYSHPLDFCPIVDTEEKKVIFIDIPNRRRKVSKHKHANFYPKHMIEKVGAMRPEAPPINVTQPEGVSFKMTGNVMEWSNFKFHIGFNYREGIVLSDVSYNDHGNVRPIFHRISLSEMIVPYGSPEFPHQRKHALDIGEYGAGYMTNPLSLGCDCKGVIHYLDAHFSDRAGDPITVKNAVCIHEEDDGLLFKHSDFRDNFATSLVTRATKLVVSQIFTAANYEYCLYWVFMQDGAIRLDIRLTGILNTYILGDDEEAGPWGTRVYPNVNAHNHQHLFSLRIDPRIDGDGNSAAACDAKSSPYPLGSPENMYGNAFYSEKTTFKTVKDSLTNYESATGRSWDIFNPNKVNPYSGKPPSYKLVSTQCPPLLAKEGSLVAKRAPWASHSVNVVPYKDNRLYPSGDHVPQWSGDGVRGMREWIGDGSENIDNTDILFFHTFGITHFPAPEDFPLMPAEPITLMLRPRHFFTENPGLDIQPSYAMTTSEAKRAVHKETKDKTSRLAFEGSCCGK
  
Inhibitor
Name:
BDBM50161135
Synonyms:
4-(aminomethyl)-N-methylpyridin-3-amine dihydrochloride | CHEMBL534914
Type:
Small organic molecule
Emp. Form.:
C7H11N3
Mol. Mass.:
137.1823
SMILES:
CNc1cnccc1CN
Structure:
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