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Target
Tissue alpha-L-fucosidase
Ligand
BDBM50065257
Substrate
n/a
Meas. Tech.
ChEBML_305486
Ki
5.3±n/a nM
Citation
 Kato, A; Kato, N; Kano, E; Adachi, I; Ikeda, K; Yu, L; Okamoto, T; Banba, Y; Ouchi, H; Takahata, H; Asano, N Biological properties of D- and L-1-deoxyazasugars. J Med Chem 48:2036-44 (2005) [PubMed]  Article 
Target
Name:
Tissue alpha-L-fucosidase
Synonyms:
Alpha-L-fucosidase 1 | FUCA1 | FUCO_BOVIN
Type:
PROTEIN
Mol. Mass.:
54093.12
Organism:
Bos taurus
Description:
ChEMBL_335897
Residue:
468
Sequence:
MRSWVVGARLLLLLQLVLVLGAVRLPPCTDPRHCTDPPRYTPDWPSLDSRPLPAWFDEAKFGVFVHWGVFSVPAWGSEWFWWHWQGEKLPQYESFMKENYPPDFSYADFGPRFTARFFNPDSWADLFKAAGAKYVVLTTKHHEGYTNWPSPVSWNWNSKDVGPHRDLVGELGTAIRKRNIRYGLYHSLLEWFHPLYLRDKKNGFKTQYFVNAKTMPELYDLVNRYKPDLIWSDGEWECPDTYWNSTDFLAWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCKDKFQPETLPDHKWEMCTSIDQRSWGYRRDMEMADITNESTIISELVQTVSLGGNYLLNVGPTKDGLIVPIFQERLLAVGKWLSINGEAIYASKPWRVQSEKNSVWYTSKGLAVYAILLHWPEYGILSLISPIATSTTKVTMLGIQKDLKWSLNPSGKGLLVFLPQLPPAALPTEFAWTIKLTGVK
  
Inhibitor
Name:
BDBM50065257
Synonyms:
(2R,3R,4R,5R,6S)-2-Hydroxymethyl-6-methyl-piperidine-3,4,5-triol | CHEMBL87474 | beta-homofuconojirimycin
Type:
Small organic molecule
Emp. Form.:
C7H15NO4
Mol. Mass.:
177.1983
SMILES:
C[C@@H]1N[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O |r|
Structure:
Search PDB for entries with ligand similarity: