Reaction Details Report a problem with these data
Target
Cytochrome c oxidase subunit NDUFA4
Ligand
BDBM50172381
Substrate
n/a
Meas. Tech.
ChEMBL_321338 (CHEMBL880622)
IC50
55±n/a nM
Citation
 Nicolaou, KC Joys of molecules. 2. Endeavors in chemical biology and medicinal chemistry. J Med Chem 48:5613-38 (2005) [PubMed]  Article 
Target
Name:
Cytochrome c oxidase subunit NDUFA4
Synonyms:
NADH-ubiquinone oxidoreductase MLRQ subunit | NDUA4_HUMAN | NDUFA4
Type:
PROTEIN
Mol. Mass.:
9374.28
Organism:
Homo sapiens (Human)
Description:
ChEMBL_321338
Residue:
81
Sequence:
MLRQIIGQAKKHPSLIPLFVFIGTGATGATLYLLRLALFNPDVCWDRNNPEPWNKLGPNDQYKFYSVNVDYSKLKKERPDF
  
Inhibitor
Name:
BDBM50172381
Synonyms:
2,2-Dimethyl-2H-chromene-6-carboxylic acid 3,4,5-trimethoxy-benzyl ester | CHEMBL370213
Type:
Small organic molecule
Emp. Form.:
C22H24O6
Mol. Mass.:
384.4224
SMILES:
COc1cc(COC(=O)c2ccc3OC(C)(C)C=Cc3c2)cc(OC)c1OC |c:17|
Structure:
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