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Target
P2Y purinoceptor 2
Ligand
BDBM50194162
Substrate
n/a
Meas. Tech.
ChEMBL_413294 (CHEMBL907213)
EC50
>1000±n/a nM
Citation
 El-Tayeb, A; Qi, A; Müller, CE Synthesis and structure-activity relationships of uracil nucleotide derivatives and analogues as agonists at human P2Y2, P2Y4, and P2Y6 receptors. J Med Chem 49:7076-87 (2006) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 2
Synonyms:
ATP receptor | P2RU1 | P2RY2 | P2RY2_HUMAN | P2U purinoceptor 1 | P2U1 | P2Y purinoceptor 2 | P2Y2 | Purinergic receptor | Purinergic receptor P2Y2
Type:
PROTEIN
Mol. Mass.:
42299.21
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1455361
Residue:
377
Sequence:
MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSRRTESTPAGSENTKDIRL
  
Inhibitor
Name:
BDBM50194162
Synonyms:
3-methyl-1-beta-D-ribofuranosylpyrimidine-2,4-dione 5'-diphosphate | CHEMBL215447 | [(2R,3S,4R,5R)-3,4-dihydroxy-5-(3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl trihydrogen diphosphate
Type:
Small organic molecule
Emp. Form.:
C10H16N2O12P2
Mol. Mass.:
418.1878
SMILES:
Cn1c(=O)ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c1=O
Structure:
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