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Target
Beta-2 adrenergic receptor
Ligand
BDBM50186613
Substrate
n/a
Meas. Tech.
ChEMBL_446237 (CHEMBL895342)
EC50
6300±n/a nM
Citation
 Buonsanti, MF; Bertinaria, M; Stilo, AD; Cena, C; Fruttero, R; Gasco, A Nitric oxide donor beta2-agonists: furoxan derivatives containing the fenoterol moiety and related furazans. J Med Chem 50:5003-11 (2007) [PubMed]  Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2_RAT | Adrb2 | Adrb2r | Adrenergic receptor beta
Type:
PROTEIN
Mol. Mass.:
46896.26
Organism:
Rattus norvegicus
Description:
ChEMBL_38603
Residue:
418
Sequence:
MEPHGNDSDFLLAPNGSRAPGHDITQERDEAWVVGMAILMSVIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWNFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYVAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHKQAIDCYAKETCCDFFTNQAYAIASSIVSFYVPLVVMVFVYSRVFQVAKRQLQKIDKSEGRFHAQNLSQVEQDGRSGHGLRSSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIRANLIPKEVYILLNWLGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSSKTYGNGYSSNSNGRTDYTGEQSAYQLGQEKENELLCEEAPGMEGFVNCQGTVPSLSIDSQGRNCNTNDSPL
  
Inhibitor
Name:
BDBM50186613
Synonyms:
4-hydroxymethyl-2-oxy-furazan-3-carboxylic acid amide | 4-hydroxymethyl-3-furoxancarboxamide | CHEMBL206100
Type:
Small organic molecule
Emp. Form.:
C4H5N3O4
Mol. Mass.:
159.1002
SMILES:
NC(=O)c1c(CO)no[n+]1[O-]
Structure:
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