Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 5
Ligand
BDBM50373633
Substrate
n/a
Meas. Tech.
ChEMBL_468024 (CHEMBL948247)
Ki
130±n/a nM
Citation
 Li, G; Stamford, AW; Huang, Y; Cheng, KC; Cook, J; Farley, C; Gao, J; Ghibaudi, L; Greenlee, WJ; Guzzi, M; van Heek, M; Hwa, JJ; Kelly, J; Mullins, D; Parker, EM; Wainhaus, S; Zhang, X Discovery of novel orally active ureido NPY Y5 receptor antagonists. Bioorg Med Chem Lett 18:1146-50 (2008) [PubMed]  Article 
Target
Name:
Neuropeptide Y receptor type 5
Synonyms:
NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor
Type:
Enzyme
Mol. Mass.:
50746.64
Organism:
Homo sapiens (Human)
Description:
Q15761
Residue:
445
Sequence:
MDLELDEYYNKTLATENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELQETFGSALLSSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSNKENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAPERPSQENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIKKRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLVSLIHCLHM
  
Inhibitor
Name:
BDBM50373633
Synonyms:
CHEMBL403622
Type:
Small organic molecule
Emp. Form.:
C19H29ClN4O3S
Mol. Mass.:
428.977
SMILES:
CN(C1CCN(CC1)S(C)(=O)=O)C(=O)NC1CCN(CC1)c1ccc(Cl)cc1
Structure:
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