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TargetCasein Kinase II
LigandBDBM50374663
Substrate/Competitorn/a
Meas. Tech.ChEMBL_469783
Ki 24±n/a nM
Citation Nie, ZPerretta, CErickson, PMargosiak, SLu, JAverill, AAlmassy, RChu, S Structure-based design and synthesis of novel macrocyclic pyrazolo[1,5-a] [1,3,5]triazine compounds as potent inhibitors of protein kinase CK2 and their anticancer activities. Bioorg Med Chem Lett18:619-23 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Casein Kinase II
Name:Casein Kinase II
Synonyms:CK II | CK2- alpha
Type:Enzyme
Mol. Mass.:39238.74
Organism:Zea mays (Maize)
Description:n/a
Residue:332
Sequence:
MSKARVYADVNVLRPKEYWDYEALTVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEKC
IIKILKPVKKKKIKREIKILQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYVNNTDFKVLY
PTLTDYDIRYYIYELLKALDYCHSQGIMHRDVKPHNVMIDHELRKLRLIDWGLAEFYHPG
KEYNVRVASRYFKGPELLVDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNHDQLVKI
AKVLGTDGLNVYLNKYRIELDPQLEALVGRHSRKPWLKFMNADNQHLVSPEAIDFLDKLL
RYDHQERLTALEAMTHPYFQQVRAAENSRTRA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50374663
NameBDBM50374663
Synonyms:CHEMBL404508
TypeSmall organic molecule
Emp. Form.C19H21N7O
Mol. Mass.363.4163
SMILESO=C1CCCCc2cnn3c(NC4CC4)nc(Nc4cccc(N1)c4)nc23
Structure
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n/a