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Target
Arginase-1
Ligand
BDBM50375814
Substrate
n/a
Meas. Tech.
ChEMBL_474406 (CHEMBL938291)
Ki
17100±n/a nM
Citation
 Kotthaus, J; Schade, D; Töpker-Lehmann, K; Beitz, E; Clement, B N(delta)-Methylated L-arginine derivatives and their effects on the nitric oxide generating system. Bioorg Med Chem 16:2305-12 (2008) [PubMed]  Article 
Target
Name:
Arginase-1
Synonyms:
ARG1 | ARGI1_BOVIN | Liver-type arginase | Type I arginase
Type:
PROTEIN
Mol. Mass.:
35008.90
Organism:
Bos taurus
Description:
ChEMBL_474406
Residue:
322
Sequence:
MSSKPQSIGVIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKELECDVKDYGDLSFADNLDDSPFQIVKNPRCVGKASEKLADVVAEVKKTGRISLVLGGDHSLAIGSISGHARVHPDLCVIWVDAHTDINTPLTTKTGNLHGQPVSFLLKELKEKMPEVPGFYWVAPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVQGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTTVAITMACFGVAREGNHKPIDYLSPPK
  
Inhibitor
Name:
BDBM50375814
Synonyms:
CHEMBL260628
Type:
Small organic molecule
Emp. Form.:
C7H16N4O4
Mol. Mass.:
220.2263
SMILES:
CN(CCC[C@H](N)C(O)=O)C(NO)N=O |r|
Structure:
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