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Target
Mu-type opioid receptor
Ligand
BDBM50376593
Substrate
n/a
Meas. Tech.
ChEMBL_477639 (CHEMBL928101)
IC50
3640±n/a nM
Citation
 Ballet, S; Misicka, A; Kosson, P; Lemieux, C; Chung, NN; Schiller, PW; Lipkowski, AW; Tourwé, D Blood-brain barrier penetration by two dermorphin tetrapeptide analogues: role of lipophilicity vs structural flexibility. J Med Chem 51:2571-4 (2008) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50376593
Synonyms:
CHEMBL409225 | SB-0304
Type:
Small organic molecule
Emp. Form.:
C25H29N5O5
Mol. Mass.:
479.5283
SMILES:
C[C@@H](N1Cc2cc(O)ccc2C[C@H](N)C1=O)C(=O)N[C@H]1Cc2ccccc2CN(CC(N)=O)C1=O
Structure:
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