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TargetCathepsin G
LigandBDBM50269858
Substrate/Competitorn/a
Meas. Tech.ChEMBL_508158
IC50 17560±n/a nM
Citation Méthot, NRubin, JGuay, DBeaulieu, CEthier, DReddy, TJRiendeau, DPercival, MD Inhibition of the activation of multiple serine proteases with a cathepsin C inhibitor requires sustained exposure to prevent pro-enzyme processing. J Biol Chem282:20836-46 (2007) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Cathepsin G
Name:Cathepsin G
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:29115.44
Organism:Mus musculus
Description:ChEMBL_508158
Residue:261
Sequence:
MQPLLLLLTFILLQGDEAGKIIGGREARPHSYPYMAFLLIQSPEGLSACGGFLVREDFVL
TAAHCLGSSINVTLGAHNIQMRERTQQLITVLRAIRHPDYNPQNIRNDIMLLQLRRRARR
SGSVKPVALPQASKKLQPGDLCTVAGWGRVSQSRGTNVLQEVQLRVQMDQMCANRFQFYN
SQTQICVGNPRERKSAFRGDSGGPLVCSNVAQGIVSYGSNNGNPPAVFTKIQSFMPWIKR
TMRRFAPRYQRPANSLSQAQT
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BDBM50269858
NameBDBM50269858
Synonyms:Trifluoro-acetate(S)-1-((1S,2S)-1-cyano-2-phenyl-cyclopropylcarbamoyl)-2-(2-fluoro-phenyl)-ethyl-ammonium
TypeSmall organic molecule
Emp. Form.C19H19FN3O
Mol. Mass.324.3715
SMILES[NH3+][C@@H](Cc1ccccc1F)C(=O)N[C@]1(C[C@H]1c1ccccc1)C#N |r|
Structure
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n/a